Intravenous anesthesia

Abstract

Anesthesia and Pain Medicine. 2003 Sept. 7(3): 105-109
ⓒ Korean Society for Intravenous Anesthesia
  
 
 
Is Elderly Patient more Sensitive to the Sedative Effect of Epidural Anesthesia?
Byung-chul Shin, M.D., So-jin Park, M.D., Hye-won Lee, M.D., Chun-hak Lim, M.D., Hae Ja Lim, M.D., Suk Min Yoon, M.D., and Seong Ho Chang, M.D.
Department of Anesthesiology and Pain Medicine, College of Medicine, Korea University
 

Background: Epidural anesthesia has been reported to have a sedative effect. In this study we investigated whether elderly patient is more sensitive to the sedative effect of epidural anesthesia than young patient using observer\'s assessment of alertness/sedation (OAA/S) scale and bispectral index (BIS) monitoring.
Methods: Twenty patients scheduled for elective lower extremity surgery were allocated to one of two groups according to age (group youg age: < 65 years of age, group old age: > 65 years of age). All patients were given epidural injection of 2% lidocaine (test dose 3 ml + 12 ml) at the L3-4 level. OAA/S scale and BIS were evaluated 5 min before and 20 min after epidural injection, respectively.
Results: Epidural lidocaine significantly decreased OAA/S scale from 5 to 4 in 70% of patients in old age group (P = 0.008), but no significant change was noticed in young age group. No significant BIS changes were noticed in both groups.
Conclusion: Elderly patient is more sensitive to the sedative effect of epidural anesthesia than young patient.
 
Key words : Bispectral index, epidural anesthesia, lidocaine, old age, propofol
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