Intravenous anesthesia


Anesthesia and Pain Medicine. 2004 Sept. 8(3): 168-171
ⓒ Korean Society for Intravenous Anesthesia
Different Interference of Isosulfan Blue Dye on Pulse Oximetries at Finger and Ear Probes
Jeong-Yeon Hong, M.D., and Soo Mie Kim, M.D.
Department of Anesthesiology, Samsung Cheil Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea

Background: Many observations have indicated that isosulfan blue (IB) dye alters the absorbent properties of blood and interferes with pulse oximetry. However, the latency, magnitude, and duration of this effect are highly variable. This study was conducted to compare the characteristics of the desaturation due to isosulfan blue dye at the finger and ear probes of oximetry.
Methods: Twenty patients with ASA class I undergoing breast cancer surgery received intradermal IB dye for sentinel node marking. The peripheral oxygen saturations were continuously monitored by the oxymeteres (Hewlett Packard-Omeda M1094B, Saronno, Italy) with reusable probes at finger and ear.
Results: SpO2 began to decrease significantly 10 min after dye injection reached a maximum decrease 4% of the baseline value at 30 min, and returned to normal in 180 min at the finger probe site. Meanwhile, at the ear probe site, SpO2 was low between 20 min and 120 min after dye injection compared to the baseline value, and the maximum decrease was 2% (P <.05). There was no decrease in SaO2 values, and vital signs and anesthetic courses were stable during the operation.
Conclusions: More delayed and less profound false desaturation at the ear probe oximetry compared with the finger probe oximetry was found after IB dye injection for sentinel node biopsy.
Key words : Isosulfan blue dye, monitoring site, peripheral oxygen saturation, sentinel node
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