Intravenous anesthesia


Anesthesia and Pain Medicine. 2001 June 5(2): 119-123
ⓒ Korean Society for Intravenous Anesthesia
Does Propofol Reduce the Incidence of Emergence Agitation after Pediatric Tonsillectomy?
Kyoung Un Kim, Jun Seok Bae, Jong Nam Lee, Young Chul Park
Department of Anesthesiology, St. Benedict Hospital, Busan, Korea.

BACKGROUND: Pediatric tonsillectomy may be associated with a high incidence of emergence agitation. Propofol anesthesia is known to reduce the incidence of emergence agitation compared with inhalation anesthesia. In this study, we examined the incidence of emergence agitation of total intravenous anesthesia (TIVA) with propofol and inhalation anesthesia with enflurane.
METHODS: Sixty children aged from 3 to 7 years undergoing tonsillectomy were randomly assigned to one of E group (enflurane-N2O, n = 30) or P group (propofol, n = 30). In group E, anesthesia was induced with 5.0 mg/kg of thiopental sodium, and then tracheal intubation was performed after administration of 0.1 mg/kg of vecuronium. Anesthesia was maintained with enflurane-O2-N2O. In group P, anesthesia was induced with 3.0 mg/kg of propofol, tracheal intubation was performed after administration of 0.1 mg/kg of vecuronium, and was maintained with continuous infusion of propofol 100 400 microgram/kg/min. Agitation was defined as inconsolable crying and combative thrashing. Exubating and emergence time were also recorded.
RESULTS: Extubating and emergence time were significantly faster in the propofol group compared with enflurane group. Incidence of agitation was significantly lower in the propofol group (3 case of 30 case, 10%) than in enflurane group (23 case of 30 case, 77%).
CONCLUSIONS: We conclude that TIVA with propofol was effective in reducing the incidence of emergence agitation following pediatric tonsillectomy compared with inhalation anesthesia.
Key words : Anesthetics, inhalation, enflurane, Anesthetics, intravenous, propofol, Complication, emergence agitation, Surgery, tonsillectomy
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